A literature review and meta- analysis on the effects of adhd medications on functional outcomes
From: Quadir I.
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Metrics details. The prevalence of ADHD in the general adult population is 2. The most frequent comorbid psychopathologies include mood and anxiety disorders, substance use disorders, and personality disorders. There are strong familial links and neurobiological similarities between ADHD and the various associated psychiatric comorbidities. The overlapping symptoms between ADHD and comorbid psychopathologies represent challenges for diagnosis and treatment. Guidelines recommend that when ADHD coexists with other psychopathologies in adults, the most impairing condition should generally be treated first.
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Attention deficit hyperactivity disorder controversies
Medications for ADHD Treatment: Research Review
Of the drugs available for attention-deficit hyperactivity disorder ADHD , the most effective and safe for short-term treatment is methylphenidate for children, and amphetamines for adults, according to the most comprehensive evidence yet from a network meta-analysis and systematic review comparing the effectiveness and safety of seven ADHD drugs against placebo, published in The Lancet Psychiatry journal. The study compared the effectiveness and side effects of amphetamines including lisdexamfetamine , atomoxetine, bupropion, clonidine, guanfacine, methylphenidate, and modafinil with each other or with placebo over 12 weeks of treatment. However, more research to confirm longer term effects of ADHD medications is urgently needed. Although they are commonly prescribed for people with ADHD, the study did not include antipsychotic drugs or antidepressants as they do not treat ADHD core symptoms. The study also does not include psychological therapies used for ADHD, but the authors say that these should be regularly discussed with people with ADHD and their family members or carers, and possibly offered before ADHD medications, if appropriate, especially for children and adolescents. More research is needed into the long-term effects of medication.
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ADHD in Teens: How Symptoms Manifest as Unique Challenges for Adolescents and Young Adults
Metrics details. Although the criteria for ADHD are well defined, the long-term consequences in adults and children need to be more comprehensively understood and quantified. We conducted a systematic review evaluating the long-term outcomes defined as 2 years or more of ADHD with the goal of identifying long-term outcomes and the impact that any treatment pharmacological, non-pharmacological, or multimodal has on ADHD long-term outcomes. Studies were identified using predefined search criteria and 12 databases. Studies included were peer-reviewed, primary studies of ADHD long-term outcomes published between January to December
We conducted a systematic review and meta-analysis to examine the effects of stimulants and atomoxetine on symptoms of EL and compare these with the effects on core ADHD symptoms. We included randomised, double-blind, placebo-controlled trials of stimulants and atomoxetine in adults aged years, with any mental health diagnosis characterised by emotional or mood instability, with at least one outcome measure of EL. All identified trials were on adults with ADHD. Results: Of the 3, publications identified, nine trials met the inclusion criteria for the meta-analysis.
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