Antidiabetic activity of medicinal plants+ thesis

From: Binu U.
Category: bhagat singh
Added: 03.04.2021
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Full text unavailable from EThOS. Thesis embargoed until 31 Jul Link to institutional repository. Traditional medicinal plants are a worthy source of secondary metabolites alkaloids, terpenoids, phenolics, flavones and polyphenols which play a vital role in the defence mechanisms of the host against pests and microbes. However, these secondary metabolites have been shown to possess potential antidiabetic, antioxidant, immunomodulatory, anti-asthmatic and anti-inflammatory activities.
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In vitro biological effects of two anti-diabetic medicinal plants used in Benin as folk medicine

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An overview of anti-diabetic plants used in Gabon: Pharmacology and Toxicology

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Metrics details. The current study was conducted to evaluate the antioxidant, analgesic, antihyperglycemic, neuropharmacological and antidiarrheal activities of ethanolic extract of Lepisanthes rubiginosa L. Quantitative and qualitative analysis were done by TLC thin layer chromatography and DPPH 1,1-diphenylpicrylhydrazyl free radical scavenging assay. Analgesic, antihyperglycemic and antidiarrheal activities were evaluated using acetic acid induced writhing in mice, oral glucose tolerance test and castor oil induced diarrhea, respectively. Neuropharmacological activity was investigated in mice using both Open Field and Hole Board methods.
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Explore traditionally used medicinal plants for diabetes mellitus would be beneficial to find an alternative option for controlling global diabetic prevalence. Present study aims to compare and identify potential antidiabetic activity in Tinospora cordifolia, Gymnema sylvestre and Aegle marmelos. Total phenolic content and anti oxidant properties were significantly different among three plants. Tinospora cordifolia ethyl acetate extract possessed significantly higher anti oxidant activity and total phenolic content. Further investigation should be conducted using higher sample size to confirm these observations.

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